Neurotoxic Mechanisms of Methylmercury: Cellular and Behavior Changes
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چکیده
Neurotoxic Mechanisms of Methylmercury: Cellular and Behavior Changes.
منابع مشابه
Biochemical Factors Modulating Cellular Neurotoxicity of Methylmercury
Methylmercury (MeHg), an environmental toxicant primarily found in fish and seafood, poses a dilemma to both consumers and regulatory authorities, given the nutritional benefits of fish consumption versus the possible adverse neurological damage. Several studies have shown that MeHg toxicity is influenced by a number of biochemical factors, such as glutathione (GSH), fatty acids, vitamins, and ...
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Depression is a heterogenous, multifaceted disorder with symptoms manifested at the psychological, behavioral and physiological level. Therefore, present study was designed as a model to analyze the long lasting effects of methylmercury chloride in male rats with a focus on depression like behavior. Male albino rats of Wistar strain were exposed orally to a dose of 2 mg/kg of methylmercury chlo...
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Mercury in both organic and inorganic forms is neurotoxic. Methylmercury (MeHg) is a commonly encountered form of mercury in the environment. Early electrophysiological experiments revealed that MeHg potently affects the release of neurotransmitter from presynaptic nerve terminals. Recently, the hypothesis that these alterations may be mediated by changes in the intracellular concentration of C...
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Methylmercury [MeHg] has long been known as a neurotoxic agent. Recent epidemiological research has also linked MeHg exposure to cardiovascular disease. However, the precise mechanisms linking MeHg toxicity to blood vessels at the cellular levels are lacking. Endothelial cells exist as a single monolayer of cells that form the inner lining of blood vessels and are crucial to the structure and f...
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For some neurotoxic chemicals, neurobehavioral effects are now considered to be among the most sensitive end points yet detected, particularly if exposures occur during critical windows of vulnerability. Chemically induced problems with perception and cognitive ability in children can be hard to identify; teasing them out of a host of genetic and sociocultural influences is a difficult task. To...
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